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Raised by her wealthy relatives, young October (Constance Cummings) balks when her guardians hand-pick her prospective husband (James Arnold). In a fit of pique, she declares that she'd sooner marry a hobo, which serves as a cue for the appearance of "gentleman tramp" Quigley (Hugh Sinclair). Forced to go through with the wedding, October is marching down the aisle when Quigley, who's been plied with liquor by the jealous bridegroom, shows up unexpectedly. The groom mockingly asks October if she still prefers the inebriated Quigley; she does, and as luck would have it, Quigley is really a nobleman in disguise. A cousin of the jilted bridegroom hires a couple of American thugs (Noah Beery, David Burns) to knock off Quigley, whereupon the film veers towards its unexpectedly melodramatic denouement. Strangers on Honeymoon is based on the equally schizophrenic Edgar Wallace yarn The Northern Tramp.