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Sally Eilers plays Sandra, a secretary who falls for her boss in this passable marital drama from Fox. The attraction is mutual and when Carter Cavendish (Ralph Bellamy) learns that his wife, Betty (Helen Vinson), is having an affair, he divorces her and marries Sandra. But Betty wants sole custody of their young daughter, Patsy (Karol Kay), a potentially wealthy child prodigy, and does what she can to embarrass her former husband. Sandra, however, calls her bluff and the greedy Betty is eventually forced to relinquish custody of the child. Second Hand Wife was based on a serialized novel by Kathleen Norris.