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In her final acting appearance, Susan Hayward is ironically cast as a research doctor who can no longer face up to the notion of dealing with death on a daily basis. Recently widowed, Dr. Maggie Cole is on the verge of giving up her job and going into seclusion. She is shaken back to reality by crusty but lovable "street doctor" Lou Grazzo (Darren McGavin), who coerces Maggie into accepting a job at a Chicago slum clinic. At first adjusting admirably to her new surroundings, Maggie undergoes a devastating assault to her emotions when she befriends a teenaged leukemia patient. Written by real-life M.D. Sandor Stern and originally telecast by ABC on September 27, 1972, Say Goodbye, Maggie Cole was supposed to have been the pilot for a weekly series, but plans for this project were abandoned after the death of star Susan Hayward.