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Big Jim Burmister (Roy Stewart) is the sheriff of a rough border town. He is taken with new arrival, half-Mexican, half-Irish Nita Valyez (Claire McDowell), as are two other men -- Carlos, a bandit and gambler (George Beranger) and the gambling house proprietor, Joe Nagle (Wilbur Higby). At first Carlos has the upper hand, but when he and Nita have a spat, he shoots up the saloon and is jailed. Nagle gives Nita the money to pay the fine, hoping that it will put him in her good graces. All it does is make his girlfriend, Lottie (Jessie Arnold), jealous and she encourages Nita and Carlos to go over the border to a town which, unbeknownst to them, is infected with the plague. Nita changes her mind, but Carlos kidnaps her and takes her anyway. Big Jim follows and finds Carlos dying of the plague, with Nita nursing him. He thinks she loves the bandit, so he leaves them and heads back for the border. But Nita realizes that it's Jim she wants after all, and follows him.