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Frasier (Kelsey Grammer) is willing to donate a huge amount of money to KACL's bike-a-thon fundraiser for AIDs research, but he balks at participating in the event. Julia (Felicity Huffman) goads Frasier into riding one of the bikes, while Daphne (Jane Leeves) does the same with Niles (David Hyde Pierce). Only one problem: Neither brother knows one end of a bike from another. Elsewhere, Daphne's mom (Millicent Martin) manages to bollix up the relationship between Martin (John Mahoney) and Cora Winston (Emily Yancy).