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Theodore Von Eltz and Robert Ober love their respective wives, Mae Busch and Marceline Day, but Busch loves only furs and jewels. Taking Day into her confidence, Busch instructs the girl in the subtle art of getting her husband Ober to indulge her every whim. But Day is more interested in her husband than in material possessions, so she forgets all about utilizing her feminine wiles and devotes herself to being a dutiful wife. Things don't work out so well for Busch, who comes to a sorry end when her husband Von Eltz finds her enjoying the favors of another man. Fools of Fashion was based on The Other Woman, a novel by George Randolph Chester.