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Lois (voice of Alex Borstein) is worried when she finds that someone has had an accident on the carpet. "How dare you sully my good name by spreading your slanderous filth!" is Stewie's (voice of Seth MacFarlane) response to the accusation. While Peter (MacFarlane) feebly works on potty training Stewie, we learn that a guilt-ridden Brian (MacFarlane) is actually responsible for the recurring messes. The truth comes out during a family visit to the supermarket. "Geez, Brian," a disgusted Peter asks, "where do you think you are, Payless?" Brian goes to see a shrink, Dr. Kaplan (voice of Sam Waterston), who believes that the poor pooch is having a midlife crisis. After traveling the globe fulfilling all his dreams, Brian returns home a new man. But when the vengeful Stewie urinates all over the house and frames Brian for the deed, the depressed dog returns to the couch, where he is told that the root of his problem is his secret love for Lois. This episode features an opening sequence in which Stewie destroys Mister Rogers' Neighborhood, but it turns out to be a dream. FOX cut this sequence from the initial airing, but it was restored when the episode was shown in reruns.