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First-year med student Lucy Knight (Kellie Martin) stumbles and bumbles her way through her first emergency-room rotation at Chicago's County General as ER launches it fifth season. Getting off to a bad start by clumsily trying to help a bleeding man on the street before her shift even begins, Lucy can't seem to do anything right at all. She manages to alienate her supervisor, the newly bearded Carter (Noah Wyle), stumbles into a clandestine romantic rendezvous, blurts out the fact that a patient is terminal to the patient's nonplussed wife, and is equally undiplomatic with a woman who may have suffered her third miscarriage. And there's still several hours of her shift to go.