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Adamo ed Eva could just as well have been titled Everyman and Everywoman. Told in episodic fashion, the film illustrates how the downfall of "Adams" throughout history have been orchestrated, either intentionally or otherwise, by the "Eves" of the world. Macario, a popular Italian comedian, portrays the film's many male protagonists, while the women are all played by Isa Barzizza. In the course of the film, director Mario Mattoli takes as many opportunities as possible to spoof then-current movie genres. Handling the productions reins of Adamo ed Eva is none other than Dino de Laurentiis.