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Academy of Motion Picture Arts and Sciences
| Nominated |
Best Actress Nell |
1994 |
| Won |
Best Actress The Silence of the Lambs |
1991 |
| Won |
Best Actress The Accused |
1988 |
| Nominated |
Best Supporting Actress Taxi Driver |
1976 |
British Academy of Film and Television Arts
| Won |
Best Actress The Silence of the Lambs |
1991 |
| Won |
Best Supporting Actress Bugsy Malone |
1976 |
| Won |
Best Supporting Actress Taxi Driver |
1976 |
| Won |
Most Promising Newcomer Bugsy Malone |
1976 |
| Won |
Most Promising Newcomer Taxi Driver |
1976 |
Hollywood Foreign Press Association
| Nominated |
Best Performance by an Actress in a Motion Picture - Drama The Brave One |
2007 |
| Nominated |
Best Performance by an Actress in a Motion Picture - Drama Contact |
1997 |
| Nominated |
Best Performance by an Actress in a Motion Picture - Drama Nell |
1994 |
| Won |
Best Performance by an Actress in a Motion Picture - Drama The Silence of the Lambs |
1991 |
| Won |
Best Performance by an Actress in a Motion Picture - Drama The Accused |
1988 |
| Nominated |
Best Performance by an Actress in a Motion Picture - Musical or Comedy Carnage |
2011 |
| Nominated |
Best Performance by an Actress in a Motion Picture - Musical or Comedy Freaky Friday |
1976 |
Independent Spirit Awards
| Won |
Best Actress Five Corners |
1988 |
Los Angeles Film Critics Association
| Won |
New Generation Award Taxi Driver |
1976 |
National Board of Review
| Won |
Best Actress The Accused |
1988 |
National Society of Film Critics
| Won |
Best Supporting Actress Taxi Driver |
1976 |
New York Film Critics Circle
| Won |
Best Actress The Silence of the Lambs |
1991 |
Screen Actors Guild
| Won |
Best Actress Nell |
1994 |
