- Her father, Roberto Cantoral, was a famous and prolific Mexican songwriter.
- Made her TV debut at the age of 11 on the thriller series La telaraña.
- Has appeared on many telenovelas, beginning with La pícara soñadora and Muchachitas in 1991.
- Cohosted the Billboard Latin Music Awards in 2002.
- Dabbled in music, releasing the album Itati Cantoral—Canta a Roberto Cantoral in 2004.
- Her stage roles have included Sally Bowles in Cabaret at Mexico City's Teatro Insurgentes; and Annie Wilkes in a 2012 production of Misery (based on the Stephen King novel).